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dr Anthony Fauci, the White House chief medical adviser, cautioned against making assumptions about the global monkeypox outbreak, citing decisions made in the early days of the HIV-AIDS epidemic.
In an article published in the New England Journal of Medicine, Fauci and Dr. H. Clifford Lane that the emerging epidemiological pattern of cases bears a “stunning resemblance” to early cases of HIV/AIDS — including most monkeypox cases in this outbreak were found in men who have sex with men.
The virus typically spreads through direct contact between the lesion and the skin, and the researchers noted that evidence supports transmission requiring prolonged or repeated exposure.
People can also become infected through contact with infected clothing or bedding.
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In particular, health officials have stressed that the virus is not considered a sexually transmitted infection, although men at high risk of the disease are advised to reduce the number of their sexual partners and refrain from group or anonymous sex.
During the HIV-AIDS pandemic, the two realized that the microorganism that causes the disease was unknown and, unlike today, countermeasures such as vaccines were not available.
“Given how little we know about the epidemiological features of the current outbreak, it is prudent to note an observation made in the first year of the HIV/AIDS pandemic: ‘…any assumption that it is specific to a segment of our Society will remain limited is really an assumption with no scientific basis.’ Therefore, additional detailed epidemiological and observational cohort studies, serosurveys, and ongoing surveillance of new cases are critical,” urged Fauci and Lane, who serve as NIAID associate director of clinical research and special projects. Fauci is leaving his position as senior White House medical adviser and NIAID director in December.
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They said the challenge for the future is to ensure efficient and equitable availability and distribution of countermeasures, as well as conducting rigorous studies needed to define clinical efficacy, identify potential safety concerns, and guide proper use.
“The lessons learned during the responses to AIDS and COVID-19 should help us organize a more efficient and effective response to monkeypox, and the response to monkeypox, in turn, should help inform our response to the inevitable next emerging or recurring infectious disease.” with pandemic potential,” the couple concluded.
According to the Centers for Disease Control and Prevention, there are nearly 17,000 confirmed cases of monkeypox and orthopoxviruses in the US and 46,724 cases worldwide.
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The number of cases reported worldwide fell by 21% in the last week, according to the World Health Organization.
The Associated Press contributed to this report.